What physiological role does ghrelin play in the body?

Prepare for the NBME Form 28 Test with flashcards and multiple choice questions, each with hints and explanations for better understanding. Maximize your study efficiency and get ready to pass your exam!

Ghrelin is often referred to as the "hunger hormone," and its primary physiological role is to stimulate appetite. It is produced mainly in the stomach and released into the bloodstream when the stomach is empty, signaling the brain to promote the sensation of hunger. This process is crucial for initiating food intake and regulating energy balance. Ghrelin levels increase before meals and decrease after eating, reflecting its role in meal initiation and adjusting energy intake according to the body's needs.

The other roles mentioned, such as regulating blood glucose or promoting digestion, are primarily associated with other hormones and processes in the body. For example, insulin and glucagon are more directly involved in blood glucose regulation, while digestive enzymes and hormones like gastrin play a prominent role in promoting digestion. Therefore, the specific function of ghrelin as an appetite stimulant is distinct and critical for understanding its role in energy homeostasis and feeding behavior.

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