In a case of suspected stroke from atrial fibrillation, which therapy would be most beneficial in the acute phase?

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In the context of a suspected stroke caused by atrial fibrillation, the administration of fibrinolytic therapy in the acute phase can be highly beneficial. Atrial fibrillation increases the risk of embolic strokes due to the formation of blood clots in the heart, which can travel to the cerebral circulation.

Fibrinolytic therapy works by dissolving the clot that is obstructing blood flow to the brain, thus potentially reversing the neurological deficits caused by the stroke. This treatment is generally indicated within a specific time window from the onset of symptoms—typically within three to four and a half hours—and can lead to improved outcomes, including functional recovery and reduced long-term disability.

In addition to the acute management of stroke, it's crucial to employ secondary prevention strategies for patients with atrial fibrillation after the acute phase, such as anticoagulation, to decrease the risk of future strokes. This indicates the importance of prompt recognition and treatment of ischemic stroke, especially in patients with underlying conditions like atrial fibrillation.

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