A female newborn diagnosed with a congenital diaphragmatic hernia is at risk for which significant respiratory condition?

In the case of a congenital diaphragmatic hernia (CDH), the significant respiratory condition the newborn is at risk for is pulmonary hypoplasia. Congenital diaphragmatic hernia occurs when there is an abnormal opening in the diaphragm, allowing abdominal contents to move into the thoracic cavity. This displacement can compress the developing lung tissue on the affected side, leading to underdevelopment, or hypoplasia, of the lungs. As a result, the lungs may have reduced volume and inadequate surface area for gas exchange, which significantly impacts the newborn's ability to breathe effectively after birth.

Pulmonary hypoplasia is a direct consequence of the mechanical issues caused by the hernia. The lungs are unable to grow properly during fetal development, leading to serious respiratory complications. Newborns with CDH commonly require immediate intervention and support to manage this condition, as it can lead to respiratory distress shortly after delivery.